Lee’s research team “stumbled” on the discovery after investigating a “gene desert”, a stretch of DNA on chromosome 21 that does not code for proteins, which has previously been linked to IBD and other autoimmune diseases. Writing in Nature, they describe how they found a section of DNA that behaves like a volume control for nearby genes. This “enhancer” was seen only in immune cells called macrophages where it boosted a gene called ETS2 and ramped up the risk of IBD.
Sounds like more “junk” non-coding DNA turns out to be not junk after all. I wonder how much of our DNA is actually junk, and how much we just don’t know yet.
Modern scientific consensus is largely that “junk” DNA isn’t a thing. All of our DNA has purpose including and sometimes especially the non-coding(nc) parts. The ncRNAs made from ncDNA come in various flavors and are very important to a lot of gene expression control. As seen here that’s ETS2 but pretty much all known genes have ncRNA that affects expression in one way or another.
Biology at a research level has basically had to throw out the DNA->RNA->protein dogma because they all affect each other and themselves.
Well, there’s things like “jumping genes” that don’t necessarily provide anything for the organism, but that’s a bit of a nitpick, since they’re not just random codons, and some do or at least could.
Think they would be able to make some sort of artificial FMT. Probiotics aren’t enough.
I know personally I have taken a boat load of antibiotics as a child and I took some for Cellulitis which because it was a skin infection required a high daily dose, never been the same since.
yeah I mean the mRNA tech of the vaccines has other potentiall amazing applications like replacing enzymes people are missing or introducing new ones. It’s temporary, so much safer than permanent gene therapy. Realistically speaking, how else are we going to remove the microplastic?
A particularly aggressive form of colorectal cancer runs in my family. My grandmother, an aunt, and other relatives have all died of it in their fifties.
This is still at the clinical trial stage, but the approach could work for many other types of cancer too. Fingers crossed it’s as successful as possible, and available as a treatment very soon.
Congrats rich fucks. You earned a first class ticket to the longest period of suffering. Us poors will die much sooner than you and won’t be around to feel the very worst of it, but you will. You earned every painful second of it. Enjoy your money while you can. Make sure you eat well and exercise. I want you fucks fit to live long enough in your bunkers to face the unstoppable hell you created. Too bad no one will be around to spit on your sun blasted corpse.
Look at fucking Trudeau and Poilievre.
WW3 is looming, China is bring openly aggressive. Russia is actively attacking the soverignty of the Baltic nations and is razing Ukraine. The western provinces are burning and in severe drought. The eastern provinces are dead husks rife with corruption.
Their top priorities are selling bitumen to China and gifting full citizenship to illegal immigrants, not even vetting them.
theguardian.com
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