Bowel disease breakthrough as researchers make ‘holy grail’ discovery (www.theguardian.com)
AI used to predict potential new antibiotics in groundbreaking study: Algorithm to mine ‘the entirety of the microbial diversity’ on Earth, speeding up antibiotic resistance research. (www.theguardian.com)
NHS patients in England to be offered trials for world-first cancer vaccine (www.theguardian.com)
A patient in England has received the world's first personalized cancer vaccine that gets his immune system to fight his colorectal cancer. (www.theguardian.com)
Economic damage from climate change six times worse than thought (www.theguardian.com)
Microplastics found in every human testicle in study (www.theguardian.com)
Eagles shifting flight paths to avoid Ukraine conflict, scientists find (www.theguardian.com)
Vulnerable birds deviating from migratory routes by up to 155 miles, which could affect breeding
Ukraine war briefing: Kharkiv campaign won’t deliver major Russian breakthrough – Nato general (www.theguardian.com)
Ukraine accuses invaders of killing civilians and setting up human shields; sanctions over North Korean arms supply to Russia. What we know on day 814
The families risking everything to keep Ukraine’s trains running – photo essay (www.theguardian.com)
Dutch photographer and multimedia journalist Jelle Krings revisits the families that have kept a war-torn country moving, despite the Russian onslaught and in the face of great personal sacrifice
Putin and Xi announce plans to strengthen military ties in Beijing (www.theguardian.com)
Russian leader praises ‘comradely’ talks with Chinese president before concert to mark 75 years of ‘friendship’
Intensifying war increasing threat to Ukraine economy, EBRD warns (www.theguardian.com)
European Bank for Reconstruction and Development cuts growth forecasts for regions it operates in, saying war ‘casting long shadow’
Antony Blinken’s rock performance in Kyiv bar divides opinion in Ukraine (www.theguardian.com)
US secretary of state took to stage with his guitar to perform Neil Young’s Rockin’ in the Free World
Putin’s war machine reshuffle reveals his deepest fear – the rise of Kremlin rivals | Samantha de Bendern (www.theguardian.com)
By removing Sergei Shoigu and promoting key allies, Russia’s leader is shoring up the war machine he needs to justify his survival, says Samantha de Bendern of Chatham House
Lammy and Healey visit Ukraine to say Labour would keep up UK’s backing (www.theguardian.com)
Shadow foreign and defence ministers go to Kyiv ‘to ensure we take politics out of the UK’s support for Ukraine’
JCB built and supplied equipment to Russia months after saying exports had stopped (www.theguardian.com)
Exclusive: Russian customs records suggest firm owned by major Tory donor kept supplying machines after ‘voluntary pause’
The Guardian view on Russia’s new offensive: Ukraine’s allies must renew their focus | Editorial (www.theguardian.com)
Editorial: Significant advances by Vladimir Putin’s forces in the Kharkiv region must concentrate minds in the west at a critical moment
Blinken delivers message of US support to Kyiv as thousands flee Kharkiv region (www.theguardian.com)
US secretary of state promises long-awaited $60bn Ukraine aid package will make ‘real difference on battlefield’
Russia-Ukraine war: Blinken says US arms will make real difference as Russia claims advances in northern Kharkiv region – as it happened (www.theguardian.com)
Mission to Kyiv by US secretary of state comes after Congress approved long-delayed $60bn aid package; Russia claims to have captured Buhruvatka
Russia directing hackers to attack UK and west, says director of GCHQ (www.theguardian.com)
Anne Keast-Butler ‘increasingly concerned’ by growing links between Russia and proxy hacker groups that pose risk to UK
Russians having ‘tactical success’ in advance on Kharkiv, Ukraine says (www.theguardian.com)
Kyiv replaces commander overseeing north-eastern Kharkiv frontline in effort to turn the tide as fighting continues
Putin removes Sergei Shoigu as Russia’s defence minister (www.theguardian.com)
Russian president proposes replacing Shoigu, who has been defence minister for years, with Andrei Belousov, an economist
‘We tell them to go’: civilian life on the edge of Russia’s advance in eastern Ukraine (www.theguardian.com)
As Putin’s forces press towards ruined Chasiv Yar, Ukrainians try to survive under bombardment in the shadow of the frontline
Judges with machine guns: the part-time drone hunters defending Kyiv (www.theguardian.com)
The ‘Mriya’ unit made up of members of the legal profession patrols the capital region’s skies with antique weapons
EU reaches deal on using profits from Russia’s frozen assets for Ukraine (www.theguardian.com)
10% of the windfall profits will fund non-lethal aid to assuage EU member states that do not wish to fund arms